Study suggests inactivated bacteria could help prevent COVID-19

A group of Spanish researchers found that treating mice with inactivated bacteria before giving them COVID-19 reduced mortality from 60% to 25%, said a study published on Thursday.

Giving mice a mucosal immunotherapy composed of the bacteria before a COVID-19 vaccine also further increased immune responses and made the vaccine significantly more effective, suggested the data, published in the prestigious journal Frontiers in Immunology.

Unlike COVID-19 vaccines, which activate the adaptive immune system, this treatment “trained” the mice’s innate immune system to go after viruses more effectively.

The innate immune system is the body’s first line of defense against unwanted pathogens. It does not create specific antibodies for each virus but instead broadly springs into action whenever challenged.

The same bacteria, called MV130, has already been shown to be clinically effective at preventing recurrent wheezing in children that was mostly triggered by other viruses. In the same trial, the results of which were published in August, data suggested that the treatment also enhanced immune responses against influenza viruses.

“Our results indicate that mucosal immunotherapy with MV130 represents a promising new tool to fight the tremendous global challenge represented by new emerging viruses, exemplified by SARS-CoV-2,” said the peer-reviewed study.

Source: Anadolu Agency

Google to pay AFP for online content in 5-year deal

Google signed a five-year agreement with Paris-based international news agency Agence France-Presse (AFP) to pay for its news content.

The agreement becomes one of the largest deals for licensing in the news industry, enabled by new legislation in France.

The deal was based on “remuneration of neighboring rights” under French law, AFP said in a statement, adding it follows months of negotiations within the framework set by the French Competition Authority.

The agreement will also include other projects, including a program for fact-checking, about which details will be shared soon.

News organizations have been losing advertisement revenue to online companies for years, as popular social media platforms use stories without payment.

“This agreement is a recognition of the value of information. This will contribute to the production of quality information and the development of innovation within the Agency,” AFP CEO Fabrice Fries said in a statement.

Google signed a three-year agreement with members of France’s press alliance in January, but the company was fined €500 million ($568 million) by the French Competition Authority in July for failing to negotiate “in good faith” amid the use of copyright content.

Source: Anadolu Agency

Germany to impose restrictions on unvaccinated

Germany’s federal and state governments agreed Thursday on new coronavirus measures, including tougher restrictions for those who are unvaccinated amid record cases.

Decisions were made during a videoconference meeting between Chancellor Angela Merkel, likely successor Olaf Scholz and premiers of 16 federal states.

Federal states will put in place tougher measures if COVID-19 hospitalization rates exceed agreed on benchmarks in their regions.

If the rate exceeds three per 100,000 people, the state will introduce the “2G rule” and allow only those who are vaccinated and those who have recovered to indoor public spaces, like restaurants, cafes and cultural facilities.

In the case of a hospitalization rate above nine per 100,000 people, federal states will apply tougher rules and restrict personal contact in public spaces.

Currently, in 12 federal states, including Bavaria, Saxony and Thuringia, the hospitalization rate exceeds three per 100,000.

The premiers also called for mandatory vaccinations for certain employees in the health sector, including staff at hospitals and nursing homes, who work with vulnerable populations.

Germany hit its highest daily number of coronavirus cases on Thursday since the pandemic began last year, as officials warned that hospitals were now at the limits of their capacity.

The Robert Koch Institute (RKI) reported 65,371 new infections in the last 24 hours and 264 additional virus-related deaths.

Active cases climbed to 532,600, reaching a new high in the current fourth wave of the pandemic, according to official data.

There were 3,376 seriously ill patients in intensive care units Wednesday, with 1,710 on mechanical ventilators.

Infections in Germany soared in recent weeks as people spend more time indoors during the colder months and a large part of the population remains unvaccinated.

The government’s goal has been to vaccinate at least 75% of the population to prevent an exponential rise in new infections.

But as of Thursday, 56.4 million people, or 67.8% of the population, have been fully vaccinated for COVID-19.

Germany’s overall vaccination rate lags behind many other EU members, including Portugal, Spain and Italy.

Source: Anadolu Agency

French press worry about far right threats

Thirty-five media organizations in France expressed concerns Thursday about increasing threats by the extreme right against journalists and urged authorities to take action.

In a letter published in the French newspaper, Liberation, media organizations said extreme right-wingers have been threatening and insulting journalists in recent weeks.

It noted that reporters covering activities of the far-right have been subjected to “unacceptable” unprecedented violence.

Members of the far-right tried to prevent journalists from doing their jobs and organizations are concerned about threats and violence, it said.

The letter urged the government and politicians to take measures and defend freedom of the press before the presidential election next April.

It said journalists working for the Street Press website were threatened by the far-right, targeting them with racist drawings featuring Muslims, Jews and Blacks.

And reporters were prohibited from following an event in Bordeaux that will be attended by far-right journalist and writer Eric Zemmour.

An employee of the Mediapart website, which follows activities of the far-right and conducts research on members, has received death threats for weeks, it noted.

Signatories of the letter include public broadcaster France Info, as well as AFP employees, Le Figaro, L’Express, Mediapart, BFMTV, Paris Match, RFI, RMC, RTL, LCI and Liberation.

Source: Anadolu Agency

US ‘considering’ boycott of Beijing Winter Olympics: President

US President Joe Biden said Thursday that a diplomatic boycott of the Winter Olympics in China set for February is “something we’re considering.”

The US president was responding to a reporter who asked about a boycott of the Games at the start of a bilateral meeting with Canadian Prime Minister Justin Trudeau.

When asked at a news conference on Thursday, White House spokeswoman Jen Psaki did not comment on the nature of the boycott but said the Biden administration has “serious concerns” about human rights abuses in China.

“There are a range of factors where we look at what our presence will be,” she said.

Biden’s remarks came three days after a virtual meeting with Chinese President Xi Jinping, during which the US president raised human rights abuses and a host of strains on the US-Sino relationship.

Several US lawmakers and human rights advocates have repeatedly called for a boycott of the 2022 Games.

the two leaders did not discuss the Olympics during the conversation on Monday, according to a White House statement.

Source: Anadolu Agency

Imprisoned former Georgian president reportedly faints

Former Georgian President Mikheil Saakashvili, who has been in hunger strike since his arrest in Oct.1, reportedly fainted during a meeting with his lawyers, according to his attorney.

Saakashvili’s lawyer Nika Gvaramia, who confirmed incident to local media, said Saakashvili was assisted by doctors and is now fine.

The Georgia’s penitentiary service, which runs the country’s prisons, said Saakashvili’s condition had stabilized.

Intensive care physician Guliko Kiliptari, who examined the former president, affirmed that Saakashvili’s condition is stable.

She added that laboratory tests had been sent to determine possible causes of Saakashvili’s fainting.

Saakashvili was arrested in Tbilisi on Oct. 1 after secretly returning to Georgia from eight years in exile.

The former president, who was serving his sentence in the southeastern province of Rustavi was transferred to Gldani prison hospital in the capital Tbilisi on Nov. 8 to prevent deterioration in his health due to increased risks, the penitentiary service reported.

Source: Anadolu Agency

Pfizer to supply US 10M courses of coronavirus pill for $5.3B

Pfizer announced Thursday that it reached an agreement with the US to supply 10 million treatment courses of its coronavirus oral antiviral pill for $5.29 billion.

The deal is subject to regulatory authorization from the US Food and Drug Administration (FDA), which Pfizer applied for emergency use authorization on Tuesday.

If approved, Pfizer’s PAXLOVID will become the first oral antiviral for the coronavirus.

As part of the deal, the US will get 10 million treatment courses to be delivered starting later this year and concluding in 2022, according to a statement.

“Pricing for PAXLOVID is based on the principles of advance commitment, volume, equity, and affordability. The price being paid by the U.S. government is reflective of the high committed volume of treatment courses being purchased through 2022,” it said.

Pfizer noted that it has also entered into advance purchase agreements with several countries and has initiated bilateral outreach to approximately 100 countries.

The company announced on Nov. 5 that PAXLOVID reduces the risk of hospitalization or death from the virus by 89%.

“It is encouraging to see a growing understanding of the valuable role that oral investigational therapies may play in combatting COVID-19,” Pfizer Chairman and CEO Albert Bourla said in the statement.

Source: Anadolu Agency

Over 119M coronavirus vaccine shots given in Turkey to date

Turkey has administered over 119.03 million doses of COVID-19 vaccines since it launched an immunization drive in January, according to official figures released on Thursday.

More than 55.97 million people have been given a first vaccine dose and over 49.9 million have been fully vaccinated, the Health Ministry said.

Turkey has also given third booster shots to over 11.81 million people.

The ministry recorded 22,234 new COVID-19 cases, 226 deaths, and 29,538 recoveries over the past day.

As many as 357,223 virus tests were done in the past 24 hours, the data showed.

Since December 2019, the pandemic has claimed over 5.12 million lives in at least 192 countries and regions, with more than 255.23 million cases reported worldwide, according to the US’ Johns Hopkins University.

Source: Anadolu Agency