Marriyum Aurangzeb on Twitter said the premier had been feeling unwell for the past two days, and tested positive on Tuesday.
She appealed to the people and party workers for prayers for his quick recovery.
This is the third time the prime minister has tested positive for the virus. He had previously contracted COVID-19 this January, and in June 2020.
Sharif returned to the country on Monday after a five-day private visit to London. He reached the British capital last week after attending the COP27 summit in Sharm el-Sheikh, Egypt.
Source: Anadolu Agency